Selected Publications

Temporal Single Cell Analysis of Leukemia Microenvironment Identifies Taurine-Taurine Transporter Axis as a Key Regulator of Myeloid Leukemia.
Rodems BJ, Sharma S, Baker CD, Kaszuba CM, Ito T, Liesveld JL, Calvi LM, Becker MW, Jordan CT, Ashton JM, Bajaj J
bioRxiv. 2024 May 14. Online Article

Identifying bone marrow microenvironmental populations in myelodysplastic syndrome and acute myeloid leukemia.
Kaszuba CM, Rodems BJ, Sharma S, Franco EI, Ashton JM, Calvi LM, Bajaj J
Journal of Visualized Experiments. 2023 Nov 10. PDF   Online Article

A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.
Spinler K, Bajaj J, Ito T, Zimdahl B, Hamilton M, Ahmadi A, Koechlein CS, Lytle N, Kwon HY, Anower-E-Khuda F, Sun H, Blevins A, Weeks J, Kritzik M, Karlseder J, Ginsberg MH, Park PW, Esko JD, Reya T
Nature Communications; Vol 11(1). 2020 Nov 26. PDF   Online Article

AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth.
Sari IN, Yang YG, Wijaya YT, Jun N, Lee S, Kim KS, Bajaj J, Oehler VG, Kim SH, Choi SY, Park SH, Kim DW, Reya T, Han J, Kwon HY
Oncogene. 2020 Nov 17. Online Article

An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.
Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T
Nature Cancer; Vol 1(4). 2020 Apr. PDF   Online Article

Stem cells in cancer initiation and progression.
Bajaj J, Diaz E, Reya T
The Journal of Cell Biology; Vol 219(1). 2020 Jan 06. PDF   Online Article

CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia.
Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T
Cancer Cell; Vol 30(5). 2016 Nov 14. PDF   Online Article

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya
Nature; Vol 534(7607). 2016 Jun 16. PDF   Online Article

Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia.
Kwon HY, Bajaj J, Ito T, Blevins A, Konuma T, Weeks J, Lytle NK, Koechlein CS, Rizzieri D, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T
Cell Stem Cell; Vol 17(2). 2015 Aug 06. PDF   Online Article

Fearful symmetry: subversion of asymmetric division in cancer development and progression.
Bajaj J, Zimdahl B, Reya T
Cancer Research; Vol 75(5). 2015 Mar 01. PDF   Online Article

Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia.
Zimdahl B, Ito T, Blevins A, Bajaj J, Konuma T, Weeks J, Koechlein CS, Kwon HY, Arami O, Rizzieri D, Broome HE, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T
Nature Genetics; Vol 46(3). 2014 Mar. PDF   Online Article

Notch signaling in CD66+ cells drives the progression of human cervical cancers.
Bajaj J, Maliekal TT, Vivien E, Pattabiraman C, Srivastava S, Krishnamurthy H, Giri V, Subramanyam D, Krishna S
Cancer Research; Vol 71(14). 2011 Jul 15. PDF   Online Article

The role of Notch signaling in human cervical cancer: implications for solid tumors.
Maliekal TT, Bajaj J, Giri V, Subramanyam D, Krishna S
Oncogene; Vol 27(38). 2008 Sep 01. PDF   Online Article